Effect of Momordica charantia L. Saponins on Osteoblast Proliferation and Alkaline Phosphatase Expression

doi:10.7506/spkx1002-6630-201023085

FOOD SCIENCE ›› 2010, Vol. 31 ›› Issue (23 ): 383-385.doi: 10.7506/spkx1002-6630-201023085

• Nutrition & Hygiene • Previous Articles Next Articles

Effect of Momordica charantia L. Saponins on Osteoblast Proliferation and Alkaline Phosphatase Expression

YANG Zhi-gang，SHEN Zong-gen，ZHANG Yan-ping

(College of Biology and Food Engineering, Changshu Institute of Technology, Changshu 215500, China)

Received:2010-11-23 Online:2010-12-15 Published:2010-12-29
Contact: YANG Zhi-gang E-mail:zgy@cslg.cn

Abstract

Abstract:

The present study was aimed at investigating the effect of Momordica charantia L. saponins on the proliferation and alkaline phosphatase (ALP) expression of in vitro cultivated osteoblasts of new born neonatal SD rats. The in vitro cultivation of new born SD rat (aged within 24 h) osteoblast at gradient concentrations of Momordica charantia L. saponins in MEM medium was performed, and MTT and PNPP assays were used to measure the proliferation and ALP activity of osteoblasts, respectively. Our findings suggest that Momordica charantia L. saponins promote the proliferation and ALP activity of osteoblasts in timeand dose-dependent manners.

Key words: Momordica charantia L. saponins, osteoblast, ALP

CLC Number:

R965
Q946.83

YANG Zhi-gang，SHEN Zong-gen，ZHANG Yan-ping. Effect of Momordica charantia L. Saponins on Osteoblast Proliferation and Alkaline Phosphatase Expression[J]. FOOD SCIENCE, 2010, 31(23 ): 383-385 https://doi.org/10.7506/spkx1002-6630-201023085

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Effect of Momordica charantia L. Saponins on Osteoblast Proliferation and Alkaline Phosphatase Expression

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